Annals of internal medicine
-
Meta Analysis
Benefits and Harms of Prescription Drugs and Supplements for Treatment of Clinical Alzheimer-Type Dementia.
Effects of drug treatment of clinical Alzheimer-type dementia (CATD) are uncertain. ⋯ Agency for Healthcare Research and Quality. (PROSPERO: CRD42018117897).
-
The accuracy and harms of brief cognitive tests for identifying clinical Alzheimer-type dementia (CATD) are uncertain. ⋯ Agency for Healthcare Research and Quality. (PROSPERO: CRD42018117897).
-
Biomarker accuracy for Alzheimer disease (AD) is uncertain. ⋯ Agency for Healthcare Research and Quality. (PROSPERO: CRD42018117897).
-
Eosinophilic esophagitis (EoE) is a relatively new disease that has reached an incidence similar to that of Crohn disease and ulcerative colitis. With this increased presence, greater recognition is essential. ⋯ The pathogenesis of EoE is rapidly being unraveled and is based on initiation of a type II allergic response to specific food antigens, leading to dense esophageal eosinophilia, chronic inflammation, and esophageal fibrosis. With greater familiarity and understanding of EoE, treatments are evolving, including identification and avoidance of food antigens; broad applications of topical steroids; and, eventually, pathway-specific biologic therapy.