Annals of internal medicine

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• Ann. Intern. Med. · Feb 2021

  Comment

  In CKD, dapagliflozin reduced a composite of eGFR decline, end-stage kidney disease, or CV or renal mortality.

  Heerspink HJ, Stefánsson BV, Correa-Rotter R, et al. Dapagliflozin in patients with chronic kidney disease. N Engl J Med. 2020;383:1436-46. 32970396.

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• Ann. Intern. Med. · Feb 2021

  In inpatients with COVID-19, none of remdesivir, hydroxychloroquine, lopinavir, or interferon β-1a differed from standard care for in-hospital mortality.

  Pan H, Peto R, Henao-Restrepo AM, et al. Repurposed antiviral drugs for Covid-19-interim WHO Solidarity Trial results. N Engl J Med. 2020. [Epub ahead of print.] 33264556.

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• Ann. Intern. Med. · Feb 2021

  Comment

  In adults hospitalized with COVID-19, the quick COVID-19 Severity Index predicted 24-h respiratory decompensation.

  Haimovich AD, Ravindra NG, Stoytchev S, et al. Development and validation of the quick COVID-19 Severity Index: a prognostic tool for early clinical decompensation. Ann Emerg Med. 2020;76:442-53. 33012378.

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• Ann. Intern. Med. · Feb 2021

  Comment

  In women aged 40 to 48 y, annual mammography vs. usual care reduced breast cancer mortality at 10 but not 23 y.

  Duffy SW, Vulkan D, Cuckle H, et al. Effect of mammographic screening from age 40 years on breast cancer mortality (UK Age trial): final results of a randomised, controlled trial. Lancet Oncol. 2020;21:1165-72. 32800099.

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• Ann. Intern. Med. · Feb 2021

  Editorial

  Ethical and Scientific Considerations Regarding the Early Approval and Deployment of a COVID-19 Vaccine.

  no abstract available

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