Annals of internal medicine
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Comment Meta Analysis
Antihypertensive drugs reduced risk for new-onset type 2 diabetes; effect varies by antihypertensive class.
Nazarzadeh M, Bidel Z, Canoy D, et al. Blood pressure lowering and risk of new-onset type 2 diabetes: an individual participant data meta-analysis. Lancet. 2021;398:1803-10. 34774144.
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Comment
In ischemic stroke upon wakening, IV thrombolysis or EVT improves functional outcome at 90 d.
Roaldsen MB, Lindekleiv H, Mathiesen EB. Intravenous thrombolytic treatment and endovascular thrombectomy for ischaemic wake-up stroke. Cochrane Database Syst Rev. 2021;12:CD010995. 34850380.
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Editorial Comment
The Epidemiology of Thrombosis With Thrombocytopenia Syndrome: Analogies With Heparin-Induced Thrombocytopenia.
In their article, See and colleagues reported a study of thrombosis with thrombocytopenia syndrome (TTS), also known as vaccine-induced immune thrombotic thrombocytopenia (VITT), a rare complication associated with receipt of the adenoviral-vectored COVID-19 vaccines ChAdOx1 nCoV-19 (Oxford/AstraZeneca) and Ad26. COV2. S (Janssen/Johnson & Johnson). The editorialists discuss the similarities of TTS with spontaneous heparin-induced thrombocytopenia.