Annals of internal medicine
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The American College of Physicians presents recommendations for the outpatient treatment of COVID-19 based on Sommer and colleagues' systematic review. The editorialists commend the authors of the recommendations and review for trying to summarize the rapidly evolving literature into clear practice points and discuss the challenges of continually updating reviews and associated recommendations as new evidence emerges and relevant outcomes evolve.
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Comment Meta Analysis
Statins increase muscle pain or weakness at 1 y, with an absolute excess of 11 events/1000 person-y.
Cholesterol Treatment Trialists' Collaboration. Effect of statin therapy on muscle symptoms: an individual participant data meta-analysis of large-scale, randomised, double-blind trials. Lancet. 2022;400:832-45. 36049498.
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Clinicians and patients want to know the benefits and harms of outpatient treatment options for SARS-CoV-2 infection. ⋯ American College of Physicians. (PROSPERO: CRD42022323440).
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Randomized Controlled Trial Multicenter Study
Effectiveness of an Intervention to Improve Decision Making for Older Patients With Advanced Chronic Kidney Disease : A Randomized Controlled Trial.
Older patients with advanced chronic kidney disease (CKD) face difficult decisions about managing kidney failure, frequently experiencing decisional conflict, regret, and treatment misaligned with preferences. ⋯ Patient-Centered Outcomes Research Institute (PCORI).