Annals of internal medicine

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• Ann. Intern. Med. · Dec 2023

  Randomized Controlled Trial

  Blood Pressure Effect of Traffic-Related Air Pollution : A Crossover Trial of In-Vehicle Filtration.

  Ambient air pollution, including traffic-related air pollution (TRAP), increases cardiovascular disease risk, possibly through vascular alterations. Limited information exists about in-vehicle TRAP exposure and vascular changes. ⋯ U.S. Environmental Protection Agency and National Institutes of Health.

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• Ann. Intern. Med. · Dec 2023

  Randomized Controlled Trial Multicenter Study

  Efficacy of Acupuncture for Chronic Spontaneous Urticaria : A Randomized Controlled Trial.

  The effectiveness of acupuncture for patients with chronic spontaneous urticaria (CSU), reported in a few small-scale studies, is not convincing. ⋯ The National Key R&D Program of China and the Science and Technology Department of Sichuan Province.

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• Ann. Intern. Med. · Dec 2023

  Randomized Controlled Trial

  Impact of Finerenone-Induced Albuminuria Reduction on Chronic Kidney Disease Outcomes in Type 2 Diabetes : A Mediation Analysis.

  In patients with chronic kidney disease (CKD) and type 2 diabetes (T2D), finerenone, a nonsteroidal mineralocorticoid receptor antagonist, reduces cardiovascular and kidney failure outcomes. Finerenone also lowers the urine albumin-to-creatinine ratio (UACR). Whether finerenone-induced change in UACR mediates cardiovascular and kidney failure outcomes is unknown. ⋯ Bayer AG.

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• Ann. Intern. Med. · Dec 2023

  Comment Randomized Controlled Trial

  Adding piroxicam to levonorgestrel increased emergency contraception effectiveness.

  Li RHW, Lo SST, Gemzell-Danielsson K, et al. Oral emergency contraception with levonorgestrel plus piroxicam: a randomised double-blind placebo-controlled trial. Lancet. 2023;402:851-858. 37597523.

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