Annals of internal medicine

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• Ann. Intern. Med. · Mar 2023

  Comment Randomized Controlled Trial

  In adults with acute HF, high-intensity care vs. usual care reduced a composite of death or HF readmission at 180 d.

  Mebazaa A, Davison B, Chioncel O, et al. Safety, tolerability and efficacy of up-titration of guideline-directed medical therapies for acute heart failure (STRONG-HF): a multinational, open-label, randomised, trial. Lancet. 2022;400:1938-52. 36356631.

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• Ann. Intern. Med. · Mar 2023

  Randomized Controlled Trial Multicenter Study Pragmatic Clinical Trial

  Cold Versus Hot Snare Polypectomy for Small Colorectal Polyps : A Pragmatic Randomized Controlled Trial.

  Although cold snare polypectomy (CSP) is considered effective in reducing delayed postpolypectomy bleeding risk, direct evidence supporting its safety in the general population remains lacking. ⋯ Boston Scientific Corporation.

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• Ann. Intern. Med. · Mar 2023

  Randomized Controlled Trial Multicenter Study

  Symptom and Viral Rebound in Untreated SARS-CoV-2 Infection.

  Although symptom and viral rebound have been reported after nirmatrelvir-ritonavir treatment, the trajectories of symptoms and viral load during the natural course of COVID-19 have not been well described. ⋯ National Institute of Allergy and Infectious Diseases.

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