Annals of surgery
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Randomized Controlled Trial Comparative Study Clinical Trial
Effect of topical local anesthetic application to skin harvest sites for pain management in burn patients undergoing skin-grafting procedures.
To determine if topical administration of local anesthesia, applied to fresh skin-harvest sites, reduces pain and analgesic requirements after surgery. ⋯ Topical lidocaine applied to skin-harvest sites produced an analgesic effect that reduced narcotic requirements compared with patients who received bupivacaine or placebo. Local anesthetic solutions aerosolized onto skin-harvest sites did not affect healing or produce toxic blood concentrations.