Annals of surgery
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Randomized Controlled Trial Comparative Study Clinical Trial
Randomized controlled trial of botulinum toxin versus laparoscopic heller myotomy for esophageal achalasia.
To compare laparoscopic cardia myotomy and fundoplication with botulinum toxin (BoTx) injection in patients with esophageal achalasia. ⋯ Laparoscopic myotomy is as safe as BoTx treatment and is a 1-shot treatment that cures achalasia in most patients. BoTx should be reserved for patients who are unfit for surgery or as a bridge to more effective therapies, such as surgery or endoscopic dilation.