Annals of surgery
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Randomized Controlled Trial
Perioperative synbiotic treatment to prevent postoperative infectious complications in biliary cancer surgery: a randomized controlled trial.
Use of synbiotics has been reported to benefit human health, but clinical value in surgical patients remains unclear. ⋯ Preoperative oral administration of synbiotics can enhance immune responses, attenuate systemic postoperative inflammatory responses, and improve intestinal microbial environment. These beneficial effects likely reduce postoperative infectious complications after hepatobiliary resection for biliary tract cancer.