Annals of surgery
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Randomized Controlled Trial Multicenter Study
Perioperative intravenous glutamine supplemetation in major abdominal surgery for cancer: a randomized multicenter trial.
To investigate whether perioperative intravenous glutamine supplementation may affect surgical morbidity. ⋯ Perioperative glutamine does not affect outcome in well-nourished GI cancer patients.
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Randomized Controlled Trial Multicenter Study Comparative Study
Ten-year outcome of laparoscopic and conventional nissen fundoplication: randomized clinical trial.
To compare 10 years outcome of a multicenter randomized controlled trial on laparoscopic (LNF) and conventional Nissen fundoplication (CNF), with focus on effectiveness and reoperation rate. ⋯ CNF carries a higher risk for surgical reintervention compared with LNF, mainly due to incisional hernia corrections. The 10-year effectiveness of LNF and CNF is comparable in terms of improvement of GERD symptoms, PPI use, quality of life, and objective reflux control. Consequently, the long-term results from this trial lend level 1 support to the use of LNF as the surgical procedure of choice for GERD.
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To provide a review of the world literature on laparoscopic liver resection. ⋯ In experienced hands, laparoscopic liver resections are safe with acceptable morbidity and mortality for both minor and major hepatic resections. Oncologically, 3- and 5-year survival rates reported for hepatocellular carcinoma and colorectal cancer metastases are comparable to open hepatic resection, albeit in a selected group of patients.
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Randomized Controlled Trial Comparative Study
Biliary reconstruction using a side-to-side choledochocholedochostomy with or without T-tube in deceased donor liver transplantation: a prospective randomized trial.
The biliary anastomosis is still one of the major causes for morbidity after orthotopic liver transplantation. The optimal method of reconstruction remains controversial. The aim of the study was to assess biliary complications after liver transplantation using a choledochocholedochostomy with or without a temporary T-tube. ⋯ This study is a large prospective randomized trial to assess biliary complications that occur following liver transplantation, after anatomizing the bile duct with or without T-tubes. A significant increased rate of complications in the group without T-tube insertion was observed. In summary, our results indicate that the usage of T-tubes is safe and an excellent tool for the quality control of biliary anastomoses.