Annals of surgery
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Randomized Controlled Trial Multicenter Study Comparative Study
Out-of-hospital hypertonic resuscitation after traumatic hypovolemic shock: a randomized, placebo controlled trial.
To determine whether out-of-hospital administration of hypertonic fluids would improve survival after severe injury with hemorrhagic shock. ⋯ Clinical Trials.gov, NCT00316017.
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Review Comparative Study
Update on the comparative safety of colloids: a systematic review of clinical studies.
To provide an updated systematic review on the comparative safety of colloids based on recent clinical studies. ⋯ Albumin displayed a more favorable safety profile than HES. Available evidence does not support the existence of consistent safety differences between HES solutions.
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Randomized Controlled Trial
Skeletal muscle is anabolically unresponsive to an amino acid infusion in pediatric burn patients 6 months postinjury.
To evaluate leg muscle, whole-body muscle, and whole-body nonmuscle protein response to anabolic signaling of amino acids in pediatric burn patients at 6 months after injury. ⋯ In pediatric burn patients at 6 months postinjury, leg muscle protein net deposition is unresponsive to amino acid infusion; and whole-body protein breakdown is significantly higher than in the control group.
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To assess what proportion of surgical malpractice claims might be prevented by the use of a surgical safety checklist. ⋯ Nearly one-third of all contributing factors in accepted surgical malpractice claims of patients that had undergone surgery might have been intercepted by using a comprehensive surgical safety checklist. A considerable amount of damage, both physical and financial, is likely to be prevented by using the SURPASS checklist.
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Comparative Study
Optimizing surgical care of colon cancer in the older adult population.
We have undertaken the current study to evaluate factors that correlate with postoperative complications in older patients undergoing surgery for colon cancer. ⋯ Identification of preoperative factors that predispose patients to postoperative complications could allow for the institution of protocols that may decrease these events. Furthermore, expanding the role of laparoscopy in the treatment of older patients with colon cancer may decrease rates of postoperative complications.