Annals of surgery
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Review Meta Analysis
Preoperative glucocorticoid use in major abdominal surgery: systematic review and meta-analysis of randomized trials.
To determine the clinical safety and efficacy of preoperative glucocorticoid (GC) administration in major abdominal surgery with regards to short term outcomes. ⋯ Preoperative administration of GCs decreases complications and LOS after major abdominal surgery as a likely consequence of attenuating the postsurgical inflammatory response. There is no evidence of increased complications in colorectal surgery.