Annals of surgery
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Comparative Study
Outcomes of Graves' Disease Patients Following Anti-Thyroid Drugs, Radioactive Iodine or Thyroidectomy as the First-Line Treatment.
The long-term outcomes of first-line choice among ATD, RAI, and thyroidectomy for GD patients remain unclear. ⋯ GD patients who received surgery as an initial treatment appeared to have lower chances of all-cause mortality, CVD, AF, psychological disease, diabetes, and hypertension in the long-term when compared to those treated with ATD or RAI. The surgery group had the lowest relapse and direct healthcare costs among the 3 treatment modalities. This long-term cohort study suggested surgery may have a larger role to play as an initial treatment for GD patients.
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We developed and validated a nomogram predicting the likelihood of occult lymph node metastases in surgically resectable esophageal cancers. ⋯ We created a nomogram predicting the likelihood of pathologic lymph node involvement in patients with esophageal cancer who are clinically node negative using a generalizable dataset. Risk stratification with this nomogram could improve delivery of appropriate perioperative care.
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Randomized Controlled Trial Comparative Study
A Randomized Controlled Trial of Endovenous Laser Ablation Versus Mechanochemical Ablation With ClariVein in the Management of Superficial Venous Incompetence (LAMA Trial).
This RCT compares the clinical, technical and quality of life outcomes after EVLA and MOCA. ⋯ Both EVLA and MOCA were highly efficacious in treating SVI; patients improved significantly in terms of disease severity, symptoms, and QoL. Both resulted in low procedural pain with a short recovery time. Axial occlusion rates were higher after EVLA. Long term follow-up is warranted to assess the effect of recanalization on the rate of clinical recurrence.