Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
-
J Coll Physicians Surg Pak · Dec 2020
Tissue Nuclear Matrix Protein Expression 22 in Various Grades and Stages of Bladder Cancer.
To study the tissue nuclear matrix protein 22 (NMP22) expression in bladder carcinoma biopsy and correlate it with prognostic factors like stage and grade of bladder cancer. ⋯ A total of 95 paraffin blocks of bladder carcinoma biopsies with data were retrieved for the study. NMP22 was expressed immunohistochemically in 87/95(91.6%) of cases and was negative in 8/95(8.4%) of cancers. Correlation of intensity of NMP22 staining with histologic grade showed that 58.3% of high grade BC expressed NMP22 strongly, 23.6% moderately and 11.1% weakly. In low grade tumors, no biopsy (0/23) expressed strong expression. Moderate intensity in 8.69% and weak in 78.26% of tumors (p<0.001). Intensity of staining with stage of tumor association revealed that 40.8% of stage I tumor showed strong staining, 16.9% moderate, and 32.3% weak staining pattern. In stage II tumors 54.1% showed strong, 29.1% moderate, and 12.5% weak NMP 22 expression. (p=0.148). Conclusion: NMP 22 is highly expressed in urinary bladder carcinoma and in male patients. It has strong association with grade and weak association with stage of tumor. Immunohistochemical expression of this protein can help in better detection and prognostic prediction of bladder carcinoma. Key Words: Bladder carcinoma, Grade, Immunohistochemistry, NMP22, Stage.
-
J Coll Physicians Surg Pak · Dec 2020
Relationship between Abdominal Aortic Calcification, Abdominal Adiposity, and Liver Density.
To identify any relationship among visceral adipose tissue area (visceral FA), liver density (liver HU), psoas muscle area (psoas MA), waist circumference (WC) and the presence and severity of abdominal aortic calcific atherosclerosis (AAC). ⋯ Psoas muscle area, visceral adiposity and waist circumference can be used to predict abdominal aortic calcification. Key Words: Visceral adipose tissue, Subcutaneous adipose tissue, Fatty liver.
-
J Coll Physicians Surg Pak · Dec 2020
Quality Assurance Audit of Digital Intraoral Periapical Radiographs at the Undergraduate Dental Clinics.
To assess the quality of digital intraoral periapical radiographs by investigating the percentage of radiographic images that satisfied the good quality standards. ⋯ According to the results of the quality assurance audit, the radiographs were below the standards set by the Health Protection Agency. Recommendations were made for improvement measures in the radiology department, and re-audit was planned after one year. Key Words: Quality assurance, ALARA, Radiation protection, Audit, Digital dental radiography.
-
J Coll Physicians Surg Pak · Dec 2020
A Combination Technique for Accurate Location and Debridement of Pathological Lesion in Femoral Head.
Debridement with bone grafting is a feasible and effective joint preserving method for early stage avascular necrosis and benign tumor of the femoral head before collapse. Although common CT and X-ray guide techniques were helpful, high dose of intraoperative radiation, inaccurate intraoperative location of pathological region, unverifiable of debridement, and longer operative duration still challenge the surgeons during the operation. ⋯ This method has not been described in previous literature. Key Words: 3-D navigation, Endoscopy, Femoral head, Debridement.
-
J Coll Physicians Surg Pak · Dec 2020
Observational StudyPrognostic Factors in Male Breast Cancer: A Single Centre Experience.
To determine the prognostic factors by assessing the clinicopathological characteristics of the male patients with breast cancer (MBC). ⋯ Advanced age might be an independent poor prognostic factor for patients with MBC. Key Words: Breast cancer, Elderly, Male, Prognosis.