Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Jan 2020
Comparative StudySignificance of Serum NT-proBNP and Endogenous H₂S for Predicting Coronary Artery Lesions in Pediatric Kawasaki Disease.
To determine the expression levels and clinical significance of serum N-terminal pro-brain natriuretic peptide (NT-proBNP), hydrogen sulfide (H₂S) and interleukin-6 (IL-6) in children with Kawasaki disease (KD). ⋯ NT-proBNP and IL-6 levels rise and the H2S level decreases in the blood of KD children, indicating that these indicators may participate in the pathogenesis of KD and that their levels are related to CAL occurrence and the vascular inflammatory response.
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J Coll Physicians Surg Pak · Jan 2020
Can Urodynamic Findings of Overactive Bladder Determine the Treatment Effect of Urotherapy in Children?
To assess the correlation between urodynamic study findings and urotherapy treatment response in children with urotherapy-resistant overactive bladder (OAB). ⋯ Urodynamic verification of DO is not a prerequisite for urotherapy treatment response. Decreased cystometry bladder capacity (DCBC) found in UDS may suggest a poorer treatment response to urotherapy than patients with normal CBC.
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J Coll Physicians Surg Pak · Jan 2020
Randomized Controlled TrialComparison of Curative Effects between Minimally Invasive Percutaneous Lag Screw Internal Fixation and Reconstruction Plate for Unstable Pelvic Fractures.
To compare the clinical efficacy of minimally invasive percutaneous lag screw internal fixation and reconstruction plate in the treatment of unstable pelvic fractures. ⋯ Compared with reconstruction plate, minimally invasive percutaneous lag screw internal fixation has better clinical efficacy in patients with unstable pelvic fractures; meanwhile, it can effectively increase serum ALP level, reduce the levels of inflammatory cytokines TNF-α and CRP, and effectively reduce surgical trauma as well as postoperative body stress response.
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J Coll Physicians Surg Pak · Jan 2020
Randomized Controlled TrialEffects of Propranolol in Accelerating Wound Healing and Attenuation of Hypermetabolism in Adult Burn Patients.
To compare the mean duration of wound healing and attenuation of muscle wasting in adult burn patients treated with propranolol and control group. ⋯ Propranolol administration in adult burn patients appears to be beneficial in reducing morbidity, mortality and hospital stay by enhancing earlier wound healing and attenuating the catabolic muscle wasting in response to stress caused by burn.
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J Coll Physicians Surg Pak · Jan 2020
Comparative StudyOutcome of Humeral Shaft Fracture Treated with Intramedullary Nail and Plate Fixation.
To compare the results of the intramedullary nail (IMN) and compression plate fixation performed for humeral shaft fracture as to determine a better option out of the two. ⋯ IMN fixation led to a significant decrease in intraoperative blood loss, shorter operating time, hospital stay, union time, and a lower rate of overall complications. Thus, IMN may be a better choice of internal fixation as it also accelerates the patients' recovery, and increases their satisfaction.