Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Dec 2021
Survival and Prognostic Factors in Limited-stage Small-cell Lung Cancer.
To evaluate the factors affecting overall survival (OS) and progression-free survival (PFS) in patients with limited stage-small cell lung cancer (LS-SCLC). ⋯ In this study, younger age, better ECOG status, stage I-II disease, and complete response to CRT had a favourable impact on OS and PFS in LS-SCLC. In addition, PCI has been shown to increase survival in these patients. Key Words: Limited-stage, Small-cell lung cancer, Thoracic radiotherapy, Chemoradiotherapy.
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J Coll Physicians Surg Pak · Dec 2021
Surgical Management of Subclavian and Proximal Axillary Artery Injuries.
Subclavian and proximal axillary arterial injuries are rare and difficult to manage. Eight patients were managed from January 2008 to December 2018 at The Aga Khan University Hospital, Karachi, Pakistan with mean age of 36.13 ± 14.48 years. All patients had penetrating injuries, from gunshot in 5 (62.5%), bomb blast in 2 (25%), and stab wound in 1 (12.5%) case. ⋯ Three (37.5%) patients had false aneurysm, while 5 (62.5%) had transected artery. Primary repair was performed in 2 (25%) cases, while 6 (75%) patients were treated with interposition graft with polytetrafluoroethylene (PTFE). All patients have salvaged limbs with good functional outcomes. Key Words: Subclavian artery, Penetrating injury, Vascular trauma, Vascular repair.
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To describe the spectrum of small intestine gastrointestinal stromal tumour (GIST) cases; and to analyse prognostic factors. ⋯ The OS ratio and OS duration were not as high as expected for small intestine GIST cases. Tumour diameter, mitotic index, and risk classification may not provide sufficient information for prognosis prediction in some cases. The frequency of recurrence and/or metastasis was higher than expected - although complete resection was achieved. Key Words: Gastrointestinal stromal tumours, Small intestine, Tumour diameter, Mitotic index.
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J Coll Physicians Surg Pak · Dec 2021
Observational StudyRole of Citicoline in Treatment of Moderate to Severe Birth Asphyxia: A Pilot Project.
An observational cohort study was performed at Neonatal Intensive Care Units of two military hospitals to see the effects of citicoline in neonates diagnosed to have moderate to severe hypoxic ischemic encephalopathy. Twenty newborns fulfilling the inclusion criteria were selected for the study and were given injection citicoline via the IV route. ⋯ Citicoline was found promising in treatment of newborns with moderate to severe birth asphyxia. Key Words: Hypoxia, Ischemia, Birth asphyxia, HIE.
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J Coll Physicians Surg Pak · Dec 2021
Intriguing Localisation of "Pacinian Neuroma''
Diagnosed at Intraoperative Consultation during Whipple Procedure.Null.