Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Feb 2021
Meta AnalysisEfficacy of Standardised Treatments Combined with Ubenimex in Patients with Malignant Tumors.
Ubenimex is widely used as an immunomodulator in the treatment of leukemia and non-small cell lung cancer to improve the anti-tumor treatment effect. However, there has not been any multicenter randomised controlled trials to study its impact on the prognosis of cancer patients. The authors aimed to conduct a meta-analysis to initially study these issues. ⋯ Between the ubenimex group and the control group, the 1-year OR was 1.40 (95% CI = 1.06 to 1.85), the 2-year OR was 1.43 (95% CI = 1.08 to 1.89) and the 3-year OR was 1.39 (95% CI = 1.07 to 1.81). Standardised treatments combined with ubenimex may improve the survival rate of patients with malignant tumors. Key Words: Malignant tumors, Ubenimex, Randomised controlled trials, Meta-analysis.
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J Coll Physicians Surg Pak · Feb 2021
Randomized Controlled TrialConcomitant Therapy versus Triple Therapy: Efficacy in H. Pylori Eradication and Predictors of Treatment Failure.
To compare concomitant therapy (CT) and triple therapy (TRT) for success in helicobacter (H.) pylori eradication and identify factors associated with treatment failure. ⋯ CT achieves better H. pylori eradication than TRT. Older age, longer duration of illness, and previous proton pump inhibitor use were independent predictors of H. pylori treatment failure. Key Words: Concomitant therapy, Eradication, H. pylori, Triple therapy.
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J Coll Physicians Surg Pak · Feb 2021
Assessing the Adherence of Operative Notes for Laparoscopic Appendectomy with the Royal College of Surgeons Guidelines.
Objective: To determine the frequency of adherence of laparoscopic appendectomy operative notes with the Royal College of Surgeons (RCS) guidelines at the tertiary care centre. Study Design: A clinical audit report.
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J Coll Physicians Surg Pak · Feb 2021
Scale Development Study: Readiness for Discharge from the Neonatal Intensive Care Unit and Home Care of Premature Infants by Parents.
To develop the readiness for hospital discharge scale for mothers and fathers with a premature infant hospitalised in the neonatal intensive care unit and to test the validity and reliability of this scale. ⋯ In line with the validity and reliability analyses, it was determined that the mother and father forms of the readiness of the parents of premature infants hospitalised in the NICU for the discharge of infants and home care scale were valid and reliable scales for measuring parents' readiness for discharge. Key Words: Parent, Premature, Neonatal intensive care units, Scale, Development, Reliability and validity.
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J Coll Physicians Surg Pak · Feb 2021
Observational StudyFactors Affecting Cervical Lymph Node Suppuration in Oropharyngeal Tularemia Cases.
To determine the factors associated with cervical lymph node suppuration in oropharyngeal tularemia. ⋯ In order to prevent suppurative lymphadenitis in oropharyngeal tularemia, it is advisable to start appropriate antimicrobials within 14 days after the appearance of symptoms. Key Words: Oropharyngeal tularemia, Cervical lymph node suppuration, Antibiotic initiation time.