Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Dec 2022
Evaluation of Viral and Bacterial Pathogens in the Central Nervous System Infections with Multiplex PCR.
To evaluate the bacterial and viral causes of central nervous system (CNS) infection by multiplex PCR. ⋯ Viral multiplex PCR, Bacterial multiplex PCR, Bacteria culture.
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J Coll Physicians Surg Pak · Dec 2022
Case ReportsHerpes Simplex Virus Encephalitis: An Unexpected Outcome in a Polytrauma Patient.
An 84-year male was brought in the emergency after a road traffic accident leading to polytrauma with deteriorating consciousness. Prolonged unexplained unconsciousness led to cerebrospinal fluid examination. The polymerase chain reaction (PCR) of cerebrospinal fluid (CSF) was found to be positive for HSV-1 DNA. ⋯ The reasons to suspect herpes simplex virus encephalitis (HSE) in this case were unexplained worsening level of consciousness, CSF findings suggestive of viral encephalitis along with highly deranged alanine aminotransferase (ALT) levels. This case highlights the importance of keeping a high index of suspicion for viral encephalitis in patients with risk factors, even in such a scenario of polytrauma. Key Words: Herpes simplex virus, Polytrauma, Viral encephalitis, Polymerase chain reaction.
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J Coll Physicians Surg Pak · Dec 2022
Randomized Controlled TrialTherapeutic Potential of Curcumin with and without Strengthening Exercises in Improving Rheumatoid Arthritis.
This study aimed to assess the synergistic effects of curcumin with and without strengthening exercises in rheumatoid arthritis (RA). Randomised controlled trial study was conducted from May 2021 to December 2021. Ninety patients were randomised into two groups. ⋯ There was higher significant (p<0.000) reduction in quantitative values of RF, ESR and CRP, WOMAC pain, ADLs, and stiffness readings in group A. This study will project to a screening of newer and more effective interventions to treat RA. Key Words: Curcumin, Rheumatoid arthritis, Strengthening exercises.
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J Coll Physicians Surg Pak · Dec 2022
Observational StudyCould Birth Weight to Placental Weight Ratio Predict Postpartum Haemorrhage and Neonatal Intensive Care Unit Admission?
To evaluate the usability of the ratio of birth weight to placental weight [fetoplacental ratio (FPR)] in predicting postpartum haemorrhage (PPH) and neonatal intensive care unit (NICU) admission. ⋯ Birth weight, Neonatal intensive care unit, Placental weight, Postpartum haemorrhage, Cesarean birth, Vaginal birth, Fetoplacental ratio.