Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Nov 2023
Diagnostic Accuracy of Serum Presepsin as Biomarker of Bacterial Sepsis in Paediatric Patients.
To determine the diagnostic accuracy of serum Presepsin for bacterial sepsis in paediatric patients keeping blood culture as the gold standard test. ⋯ Presepsin, Systemic Inflammatory Response Syndrome, Bacterial sepsis, Paediatric patients.
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J Coll Physicians Surg Pak · Nov 2023
Meta AnalysisEffects of Physical Activity on Thyroid Stimulating Hormone Levels in Obese Metabolic Syndrome Patients: A Meta-Analysis.
Metabolic syndrome is a combination of multiple disorders that predispose an individual to risk of diabetes, obesity, cardiovascular diseases (CVDs), cerebrovascular accidents (CVAs), and insulin-resistance. Hypothyroidism is the most prevalent metabolic disorder causing obesity, followed by hypercortisolism and hypogonadism. Hence, this study aimed to determine the effects of various exercises on thyroid stimulating hormone (TSH) levels in obese patients with metabolic syndrome. ⋯ It was concluded that although a pooled moderate effect of training on TSH levels was observed when all the studies were analysed using a continuous measure analysis SMD model, an individual analysis of the studies revealed a mild effect, with many studies also revealing the negative impact of training on TSH levels. Nonetheless, exercise-based intervention strategies are safe and effective as a management strategy for hypothyroidism and obesity due to hypothyroidism. Key Words: Thyroid hormone, Exercise, Metabolic syndrome, Obesity, TSH level.
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J Coll Physicians Surg Pak · Nov 2023
Meta AnalysisImproving Kyphotic Postures and Neck Pain in Young Adults: A Meta-Analysis of Exercise-Based Interventions.
The study aimed to review the findings concerning the effects of exercises on Cobb angle and pain in patients suffering from cervical pain caused by thoracic kyphosis. Two investigators separately conducted a systematic review of the electronic literature from 2018 till 2022. PubMed, MEDLINE, Web of Science, Science Direct, Cochrane Central Register of Controlled Clinical Trials, Google Scholar, and Scopus were among the electronic databases that were accessed. ⋯ The between-groups pooled random SMD for Cobb angle and pain showed a larger effect size of -2.146 and -1.126, respectively. The findings suggested that physical therapy exercise may result in larger changes among the Cobb angle and neck pain of kyphotic patients. Key Words: Exercise, Physical therapy, Cobb angle, Pain, Thoracic kyphotic angle, Conservative management.
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J Coll Physicians Surg Pak · Nov 2023
Frequency of TP53 Mutation in B-Cell Chronic Lymphocytic Leukaemia and its Association with Lymphocyte Doubling Time.
To determine the frequency of TP53 mutation at diagnosis of B-cell Chronic Lymphocytic Leukaemia (B-CLL) in Pakistani patients, and to investigate whether lymphocyte doubling time (LDT) of less than 1 year could be used as a surrogate marker for TP53 mutation. ⋯ TP53 mutation, B-Cell chronic lymphocytic leukaemia (B-CLL), Lymphocyte doubling time (LDT).
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J Coll Physicians Surg Pak · Nov 2023
The Impact of the COVID-19 Pandemic on the Diagnosis and Treatment Characteristics of Operated Lung Cancer Patients.
To analyse the impact of the COVID-19 pandemic on the diagnostic method, disease stage, treatment modalities, and survival of operated non-small cell lung cancer (NSCLC) patients. ⋯ Lung cancer, Incidentally, COVID-19 pandemic.