Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Jan 2023
Case ReportsType B Aortic Dissection Converted into Type A Aortic Dissection.
A young patient presented to the emergency room (ER) with Type B aortic dissection and ascending aorta aneurysm. He was planned for medical optimization, close surveillance, echocardiography, and ascending aorta replacement on an urgent basis. His surveillance echocardiogram 2 days later revealed that Type B aortic dissection has converted into Type A aortic dissection. ⋯ A 25-sized SJ aortic valve- conduit was used for root replacement. The patient did very well and got discharged from the hospital on the sixth postoperative day. Key Words: Type A aortic dissection, Aortic root and ascending aorta aneurysm, Type B aortic dissection.
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J Coll Physicians Surg Pak · Jan 2023
Case ReportsMalignant Transformation of Vestibular Schwannoma at First Occurrence without Prior Irradiation.
Intracranial malignant peripheral nerve sheath tumours (MPNST) arising from the vestibulocochlear nerve are quite rare. Due to the increasing use of stereotactic radiosurgery worldwide for benign intracranial lesions, the literature available has primarily focused on the post-radiotherapy malignant transformation of vestibular schwannomas (VSs). To date, very few cases have been reported enlightening the occurrence of MPNST without prior irradiation or a history of neurofibromatosis. ⋯ The diagnosis was low-grade MPNST arising in the background of vs. based on mitosis, loss of H3K27me3, and radiologically infiltrative borders. The main objective of this case report was to emphasise the need for a cautious assessment of VSs with hypercellularity and atypia for mitosis, necrosis and invasion to exclude malignancy. Key Words: Schwannoma, malignant peripheral nerve sheath tumour, neurofibromatosis, vestibular.
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J Coll Physicians Surg Pak · Jan 2023
Case ReportsMalignant Phyllodes Tumour with Osteoclast-type Giant Cells in Young Females: A Rare Histology and Differential Diagnoses.
Phyllodes tumour (PT) is a biphasic fibroepithelial tumour of the breast that accounts for 0.3-1% of all primary breast neoplasms. It is subdivided into benign, borderline, and malignant categories based on histologic features including stromal overgrowth, stromal hypercellularity, mitotic count, degree of atypia, and type of margins. Malignant PT (MPT) is characterised by infiltrative margins, marked stromal overgrowth, increased stromal hypercellularity, greater than 10 mitoses/10 high-power fields (HPFs), and moderate to severe atypia. ⋯ We herein report cases of MPT with OGCs in two young females who had a history of swelling in unilateral breast for two-three years. Histologic examination revealed classic phyllodes areas admixed with a sarcomatous stromal component with OGCs. Key Words: Malignant phyllodes tumour, Breast, Osteoclast-type giant cells.
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J Coll Physicians Surg Pak · Jan 2023
Case ReportsA Rare Complication of Brucellosis: A Case of Acute Cholecystitis.
Brucellosis is a common zoonotic disease in the world and in Turkiye. The disease is transmitted to humans through ingestion of unpasteurized animal milk products or direct contact with infected tissues or fluids. ⋯ Herein, we report a case of acute cholecystitis, a rare complication of brucellosis, presenting with fever, abdominal pain, and elevated liver enzymes. Key Words: Acute cholecystitis, Brucellosis, Zoonoses.