Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Jan 2024
Short-term Outcomes of Elective Abdominal Aortic Aneurysm Repair.
To evaluate the presentations, aetiologies, and outcomes (survival and morbidity) of patients who underwent abdominal aortic aneurysm (AAA) repair at a tertiary care centre in a low middle-income country (LMIC). ⋯ Abdominal aortic aneurysm repair, Low middle-income country.
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J Coll Physicians Surg Pak · Jan 2024
Role of Alanine Transaminase and Transient Elastography in Categorising Nonalcoholic Fatty Liver Disease Subgroups.
To investigate the association of alanine transaminase (ALT) with transient elastography grades to define various nonalcoholic fatty liver disease (NAFLD) groups for disease status. ⋯ Nonalcoholic fatty liver disease, Cirrhosis, Transient elastography.
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J Coll Physicians Surg Pak · Jan 2024
Observational StudyEfficacy of Neoadjuvant Chemotherapy in Lobular and Rare Subtypes of Breast Cancer.
To determine the predictive factors for the pathological complete response (pCR) in patients with non-ductal invasive breast cancer (ND-BC) receiving neoadjuvant chemotherapy. ⋯ Neoadjuvant chemotherapy, Non-ductal breast cancer, Lobular carcinoma.
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J Coll Physicians Surg Pak · Jan 2024
Review Meta AnalysisKetamine in the Management of Acute Pain: A Comprehensive Meta-Analysis.
This review was conducted to find the effectiveness and safety of ketamine in managing acute or sudden pain in the emergency scenarios. The research was carried out using databases such as PubMed, MEDLINE, Cochrane trial registries, and EMBASE from inception up to July 2022. The meta-analysis employed using the random-effects model and presented results as pooled standardised mean difference (SMD) and risk ratio (RR) alongside their 95% confidence intervals (CIs). ⋯ Pooled RR reflecting the requirement for supplementary analgaesics was 0.96 (95% CI: 0.65-1.41). The study found that ketamine's efficacy and safety were comparable or even superior to opioids in addressing sudden pain in the emergency contexts. Key Words: Ketamine, Meta-analysis, Opioids, Acute pain, Emergency.
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J Coll Physicians Surg Pak · Jan 2024
Observational StudyFrequency of Elevated Resting Heart Rate Among Young Healthy Adults with Normal BMI.
It was an observational, cross-sectional study conducted at Ziauddin University, Karachi, from 10th March to 31st August 2021, to investigate the frequency of elevated resting heart rate in healthy young adults with normal BMI. A total of 420 participants were recruited for the study with age ranging from 18-30 years. Subsequently, candidates with normal BMI ranging between 18-24 kg/m2 were selected for the evaluation of elevated resting heart rate (RHR). ⋯ This study demonstrated high frequency of RHR in a young population. Efforts are needed to control the increased RHR. Key Words: Resting heart rate (RHR), Young adults, Cardiovascular disease (CVD), BMI, Tachycardia.