Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Sep 2024
Observational StudyImpact of Microsurgery and Postoperative Radiotherapy on Neurological Function in Intramedullary Spinal Cord Gliomas.
To assess the clinical efficacy of combined microsurgery and postoperative radiotherapy for the treatment of intramedullary spinal gliomas and its impact on neurological function. ⋯ Intramedullary spinal cord glioma, Microsurgery, Neurological function, Radiotherapy.
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J Coll Physicians Surg Pak · Sep 2024
Diagnostic Accuracy of Polymerase Chain Reaction Against Giemsa Staining on Tissue Biopsy for Cutaneous Leishmaniasis.
To evaluate the diagnostic accuracy of a commercial real-time polymerase chain reaction (PCR) kit targeting 18S rRNA against Giemsa-stained tissue slides in patients clinically suspected of cutaneous leishmaniasis (CL). ⋯ Giemsa stain, Leishmania spp., Polymerase chain reaction, Viasure.
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J Coll Physicians Surg Pak · Sep 2024
Letter Case ReportsWell-Differentiated Neuroendocrine of Left Kidney.
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J Coll Physicians Surg Pak · Sep 2024
Editorial LetterNavigating the Vast Landscape of Academic Research Databases: A Guide for Researchers.
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J Coll Physicians Surg Pak · Sep 2024
Meta AnalysisInclisiran Treatment for Cardiovascular Disease Risk Reduction: A Systematic Review and Meta-Analysis.
This study was a meta-analysis of patient data to investigate the therapeutic effects of inclisiran on LDL-C, PCSK9, and TC in patients with atherosclerosis. Authors searched the Cochrane Library, Pubmed, EMBASE, and Web of Science databases for randomised controlled trials. Data of 4,731 subjects from five randomised clinical trials were included in this analysis. ⋯ They exhibited significant reductions in total cholesterol protein levels ((MD) -1.477; 95% CI -1.585 to -1.369; p <0.001; I2 = 46.7%). Inclisiran reduced LDL-C and PCSK9 levels as well as TC and Apo B levels significantly in patients with atherosclerotic cardiovascular disease (ASCVD). Key Words: Inclisiran, Low-density lipoprotein cholesterol, Atherosclerosis, Adverse events, Meta-analysis.