Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Mar 2020
Randomized Controlled TrialEffectiveness of Cefoperazone-sulbactam alone and Combined with Tigecycline in the Treatment of Multi-drug Resistant Acinetobacter Baumannii Pulmonary Infection.
The aim of this study was to compare the effectiveness of cefoperazone-sulbactam alone and combined with tigecycline in the treatment of multi-drug resistant acinetobacter baumannii pulmonary infection. It was an experimental study carried out from April 2016 to September 2018. ⋯ After 14 days of treatment, serum levels of PCT, CRP, TNF-a and IL-6 in group B were lower than those in group A (all p <0.001); APACHE II scores of group B were lower than those of group A (p <0.001). Compared with cefoperazone-sulbactam sodium alone, cefoperazone-sulbactam combined with tigecycline can effectively reduce the inflammatory response of patients with multi-drug resistant acinetobacter baumannii pulmonary infection; and thus a better prognosis can be obtained.
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J Coll Physicians Surg Pak · Mar 2020
Randomized Controlled TrialEffectiveness of Two Types of Fixed Lingual Retainers in Preventing Mandibular Incisor Relapse.
To compare and evaluate the relapse tendency of two types of fixed lingual retainers using Little's irregularity index for a follow-up of one year. ⋯ Fiber-reinforced retainers are more effective in preventing the mandibular incisor relapse. The results of the study also suggest that the irregularity of the dentition increases with the passage of time.
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J Coll Physicians Surg Pak · Feb 2020
Randomized Controlled TrialVacuum-assisted Closure in Integration of Skin Graft Over Scalp Wounds: A Randomised Control Trial.
To compare outcome of split thickness graft with and without vacuum-assisted closure over the scalp soft tissue defects in terms of graft take and complications. ⋯ Outcome of split skin graft over scalp soft tissue defects with VAC dressing is better than simple dressing in terms of graft take and complications rate.
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J Coll Physicians Surg Pak · Jan 2020
Randomized Controlled Trial Comparative StudyEffects of Butyphthalide Combined with Idebenone on Inflammatory Cytokines and Vascular Endothelial Functions of Patients with Vascular Dementia.
To determinate the clinical effect of butyphthalide combined with idebenone in the treatment of vascular dementia (VD) and the influence on inflammatory cytokines and vascular endothelial functions. ⋯ Butyphthalide combined with idebenone can effectively reduce serum inflammatory factor level of VD patients, regulate vascular endothelial functions, relieve dementia degree, and improve cognitive function and daily activity ability.
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J Coll Physicians Surg Pak · Jan 2020
Randomized Controlled TrialComparison of Curative Effects between Minimally Invasive Percutaneous Lag Screw Internal Fixation and Reconstruction Plate for Unstable Pelvic Fractures.
To compare the clinical efficacy of minimally invasive percutaneous lag screw internal fixation and reconstruction plate in the treatment of unstable pelvic fractures. ⋯ Compared with reconstruction plate, minimally invasive percutaneous lag screw internal fixation has better clinical efficacy in patients with unstable pelvic fractures; meanwhile, it can effectively increase serum ALP level, reduce the levels of inflammatory cytokines TNF-α and CRP, and effectively reduce surgical trauma as well as postoperative body stress response.