Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
-
J Coll Physicians Surg Pak · Aug 2017
Case ReportsAcute Complete Adult-onset Kawasaki Disease in a Middle-Aged Woman.
A 55-year-old Chinese lady was diagnosed with acute complete Kawasaki disease (KD) in January 2015. To our knowledge, this patient was the first described woman who was over 50 years and fulfilled all the characteristics of acute complete KD. The patient had a striking result on the 26th day since this disease onset after the initiation of treatment of immunoglobulin (IG) and aspirin; and did not have any complications up to now. The purpose of this case report was to raise the awareness of KD in the middle-aged persons and the therapeutic schedules, as there is no valid therapeutic therapeutic for adults with KD.
-
J Coll Physicians Surg Pak · Aug 2017
Prognostic Potential of N-Cadherin in Oral Squamous Cell Carcinoma via Immunohistochemical Methods.
To assess the prognostic potential for N-cadherin in oral squamous cell carcinoma and oral epithelial dysplasia. ⋯ N-cadherin can be used as a potential biomarker for early diagnosis of OSCC. However, the N-cadherin expression did not show any correlation with the histological grade of OSCC.
-
J Coll Physicians Surg Pak · Aug 2017
Soyabean Oil Supplementation Effects on Perivascular Inflammation in Lungs Induced by Bisphenol A: A Histological Study.
To determine the effect of soyabean oil supplementation on perivascular inflammation in lungs of adult mice induced by Bisphenol A(BPA). ⋯ BPAproduced perivascular inflammation and con-commitant administration of soyabean oil diet protected against it in rodent.
-
J Coll Physicians Surg Pak · Jul 2017
Determination of Mean Glycated Haemoglobin in Healthy Adults of a Local Population.
To determine the mean hemoglobin HbA1C levels of disease-free adults in a local population and its optimum cutoff for the diagnosis of diabetes. ⋯ The mean HbAIC and cutoff point for diabetes in the study population is 5.07 ±0.58% and 6.05%, respectively (AUC 0.827, 95% CI: 0.732 to 0.923, p<0.001) with 53.3% sensitivity and 98.5% specificity.
-
J Coll Physicians Surg Pak · Jul 2017
Clinical Profile and Short-Term Outcome of Pediatric Hyperleukocytic Acute Leukemia from a Developing Country.
This study was conducted to determine the frequency, clinical profile, and short-term outcome of children with hyperleukocytosis at two pediatric oncology centers in Karachi. Of a total 1,045 patients, 13.97% (n=146) patients had hyperleukocytosis. Majority (61.7%, n=90) were under 10 years of age and 76% (n=146) were male. ⋯ Infectious complications occurred in 23.2% (n=34) patients. The case-specific mortality was 20.5% (n=30). No mortality was related to early complications of hyperleukocytosis.