Annals of the rheumatic diseases
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Multicenter Study
No evidence for a role of the catechol-O-methyltransferase pain sensitivity haplotypes in chronic widespread pain.
The aim of this study was to investigate the association between the catechol-O-methyltransferase (COMT) 'pain sensitivity' haplotypes and chronic widespread pain (CWP) in two distinct cohorts. ⋯ There was no evidence of association between the COMT 'pain sensitivity' haplotypes and CWP in two population-based cohorts.