Kidney & blood pressure research
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Kidney Blood Press. Res. · Jan 2002
Randomized Controlled Trial Comparative Study Clinical TrialComparison of ondansetron with metoclopramide in the symptomatic relief of uremia-induced nausea and vomiting.
Nausea and vomiting are well-known gastrointestinal complications in chronic renal failure and are frequent indications for the commencement of dialysis. Although the administration of antiemetic drugs (metoclopramide and, recently, ondansetron) is usually mentioned, there are scanty data on their effects. ⋯ We conclude that at the dosage level studied ondansetron is about twice as effective as metoclopramide in the symptomatic relief of uremia-induced nausea and vomiting.