Tropical medicine & international health : TM & IH
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Trop. Med. Int. Health · Feb 2010
Coagulation disorders in patients with severe leptospirosis are associated with severe bleeding and mortality.
To determine the involvement of coagulation in bleeding and poor outcome in patients with severe leptospirosis. ⋯ The coagulation system was strongly activated in patients with leptospirosis. This was more pronounced in the deceased and in patients with severe bleeding than in than the survivors and in those without severe bleeding.
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Trop. Med. Int. Health · Jan 2010
Provider-initiated HIV testing for paediatric inpatients and their caretakers is feasible and acceptable.
Early diagnosis of HIV-infected children remains a major challenge in Africa. Children who are hospitalised represent an opportunity for HIV diagnosis and appropriate treatment. We introduced HIV Counselling and Testing (HCT) for hospitalised children and their caretakers in Mulago teaching hospital in Uganda to assess its feasibility. ⋯ HCT for hospitalized children and their caretakers identified a significant number of HIV infected children and caretakers. More than half of the children had advanced HIV disease. More intensive efforts are needed to ensure earlier diagnosis and linkage to care for HIV infected children.
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Trop. Med. Int. Health · Oct 2009
ReviewEpidemiology and prevention of human papillomavirus and cervical cancer in sub-Saharan Africa: a comprehensive review.
To identify the gaps of knowledge and highlight the challenges and opportunities for controlling cervical cancer in sub-Saharan Africa (SSA). ⋯ Additional data are needed to strengthen ICC as a public health priority to introduce, implement and sustain effective cervical cancer control in Africa.
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Trop. Med. Int. Health · Sep 2009
High mortality risk among individuals assumed to be TB-negative can be predicted using a simple test.
To determine mortality among assumed TB negative (aTBneg) individuals in Guinea-Bissau and to investigate whether plasma levels of soluble urokinase receptor (suPAR) can be used to determine post-consultation mortality risk. ⋯ Our study showed a high mortality rate among aTBneg individuals and demonstrated that suPAR measurements can provide prognostic information on mortality among individuals without disease diagnosis. Measuring suPAR is a technically simple method for determining mortality risk in individuals that are assumed to be TB-negative.