The journal of obstetrics and gynaecology research
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J. Obstet. Gynaecol. Res. · Dec 2013
Randomized Controlled Trial Comparative StudyOptimal timing of prophylactic antibiotic for cesarean delivery: a randomized comparative study.
Cesarean delivery is associated with a significantly higher postoperative infection rate than that following vaginal birth and other surgical procedures. This study compared whether antibiotic prophylaxis administered preoperatively was more effective in preventing infectious morbidity following cesarean delivery than administration at cord clamping. ⋯ Administration of prophylactic antibiotic at 30-60 min before skin incision resulted in better maternal outcome when infectious morbidity and postoperative hospital stay were concerned, without influencing the neonatal outcome.