Nephrology
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Randomized Controlled Trial Multicenter Study
Darbepoetin alfa once monthly corrects anaemia in patients with chronic kidney disease not on dialysis.
While darbepoetin alfa (DA) can be administered once monthly (QM) to maintain haemoglobin (Hb) concentrations in anaemic patients with chronic kidney disease not on dialysis (CKD-ND), the QM use of DA for anaemia correction has not been previously investigated. ⋯ In subjects with CKD-ND, QM dosing was non-inferior to Q2W dosing for anaemia correction and had a similar safety profile.