International journal of clinical oncology
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Int. J. Clin. Oncol. · Dec 2015
Randomized Controlled TrialEfficacy of palonosetron and 1-day dexamethasone in moderately emetogenic chemotherapy compared with fosaprepitant, granisetron, and dexamethasone: a prospective randomized crossover study.
Although palonosetron (PALO) and NK1 receptor antagonist both reduce chemotherapy-induced nausea and vomiting, no comparison trial in moderately emetogenic chemotherapy (MEC) had been reported. The purpose of this study was to find out which drug combinations are preferable for patients receiving MEC. ⋯ PALO and 1-day DEX is almost equivalent to FAPR, GRAN, and DEX for MEC.