Respirology : official journal of the Asian Pacific Society of Respirology
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Randomized Controlled Trial Comparative Study
Low-dose hydrocortisone treatment for patients with septic shock: a pilot study comparing 3days with 7days.
Although there is controversy regarding the benefit of low-dose corticosteroid therapy in patients with septic shock, the Surviving Sepsis Campaign has advocated that low-dose intravenous hydrocortisone be used to treat adult septic shock patients. This study investigated the effect of the duration of a stress dose of hydrocortisone on survival of septic shock patients with relative adrenal insufficiency. ⋯ This pilot study showed that in patients with septic shock and relative adrenal insufficiency, 28-day mortality did not differ between those treated with low-dose hydrocortisone for 3 or 7days.