Archives of disease in childhood
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Randomized Controlled Trial Clinical Trial
Rapid skin anaesthesia using high velocity lignocaine particles: a prospective placebo controlled trial.
Local anaesthetic creams (EMLA and Ametop) are used widely to provide pain free intravenous cannulation. However, they take a minimum of 45 minutes to become effective. ⋯ This prototype device appears to provide significant skin anaesthesia at the antecubital fossa, but not at the back of hand. The device is not painful to use and causes only minor short term skin changes.
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Randomized Controlled Trial Clinical Trial
Short term effects of adrenaline in bronchiolitis: a randomised controlled trial.
Airway narrowing in acute bronchiolitis does not respond to inhaled bronchodilators but does to adrenaline when compared to bronchodilators. Influences of supportive care were not considered in previous treatment studies. ⋯ No improvement was shown with inhaled adrenaline in acute bronchiolitis, when compared with supportive care or placebo. Improvements noted pretreatment question whether prior noted improvements were through supportive care or pharmacological interventions.