Archives of disease in childhood
-
Randomized Controlled Trial Multicenter Study
Restricted fluid bolus volume in early septic shock: results of the Fluids in Shock pilot trial.
To determine the feasibility of Fluids in Shock, a randomised controlled trial (RCT) of restricted fluid bolus volume (10 mL/kg) versus recommended practice (20 mL/kg). ⋯ Participants were not as unwell as expected. A larger trial is not feasible in its current design in the UK.