Health technology assessment : HTA
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Health Technol Assess · Oct 2018
Randomized Controlled Trial Multicenter StudyAdding emollient bath additives to standard eczema management for children with eczema: the BATHE RCT.
Childhood eczema is very common. Treatment often includes emollient bath additives, despite there being little evidence of their effectiveness. ⋯ Further research is required on optimal regimens of leave-on emollients and the use of emollients as soap substitutes.
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Health Technol Assess · Oct 2018
Randomized Controlled Trial Multicenter StudyAdjunctive rifampicin to reduce early mortality from Staphylococcus aureus bacteraemia: the ARREST RCT.
Staphylococcus aureus bacteraemia is a common and frequently fatal infection. Adjunctive rifampicin may enhance early S. aureus killing, sterilise infected foci and blood faster, and thereby reduce the risk of dissemination, metastatic infection and death. ⋯ Given the substantial mortality, other antibiotic combinations or improved source management should be investigated.