International journal of pharmaceutical compounding
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Fibromyalgia is a syndrome associated with chronic, widespread musculoskeletal pain, fatigue, depression, and cognitive dysfunction. With few U. S. ⋯ Based on our study results, the beyond-use date for compounded low-dose naltrexone formulations stored at room temperature and protected from light can be extended to 1 year. The longer beyond-use dating allows patients greater flexibility in using these capsules during the flare-ups associated with fibromyalgia without needing a refill immediately at the onset of symptoms. In addition, it may help compounding pharmacies reduce waste associated with small-batch preparation of these capsules.
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One is generally introduced to density in the pharmacy calculations class with exercises in converting weights to liquid measurements, etc. However, density has far more applications than that. ⋯ Density/specific gravity is used in both nonsterile and sterile compounding, as in using automated compounders for parenteral nutrition solutions. Equipment available is both manual and automated, depending upon the preferences of the user and is reasonably priced.