The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease
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Int. J. Tuberc. Lung Dis. · Oct 2011
Multicenter StudyProgrammatic management of multidrug-resistant tuberculosis: models from three countries.
Although multidrug-resistant tuberculosis (MDR-TB) is a major global health problem, there is a gap in programmatic treatment implementation. ⋯ It is recommended that all programs providing MDR-TB treatment address these six areas during program development and implementation.
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Int. J. Tuberc. Lung Dis. · Oct 2011
Recurrence after successful treatment among patients with multidrug-resistant tuberculosis.
A retrospective review was conducted of patients with multidrug-resistant tuberculosis (MDR-TB) to elucidate the rate of recurrence after successful treatment. Of 123 MDR-TB patients, 90 were declared as 'cured' or 'treatment completed' after individualised treatment; four (4.4%) experienced recurrence. All patients with recur- rent MDR-TB were documented as 'treatment completed' after treatment. Recurrence of MDR-TB is possible after successful treatment, particularly among those documented as 'treatment completed'.
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Int. J. Tuberc. Lung Dis. · Oct 2011
Translating tuberculosis research into global policies: the example of an international collaboration on diagnostics.
Using the example of an international collaboration on tuberculosis (TB) diagnostics, we mapped the key stages and stakeholders involved in translating research into global policies. In our experience, the process begins with advocacy for high-quality, policy-relevant research and appropriate funding. Following the assessment of current policy and the identification of key study areas, policy-relevant research questions need to be formulated and prioritised. ⋯ This may be one reason why there has been poor uptake of new tools by national TB control programmes despite global policy recommendations. Stronger engagement with national policy makers and donors during the research-intopolicy process may be needed to ensure that their evidence requirements are met and that global policies translate into national policies. National policies are central to translating global policies into practice.
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Int. J. Tuberc. Lung Dis. · Oct 2011
Comparative StudyUse of soluble triggering receptor expressed on myeloid cells-1 in non-tuberculous mycobacterial lung disease.
Serum biomarkers are rarely studied in patients with non-tuberculous mycobacterial lung disease (NTM-LD). ⋯ In patients with respiratory specimens that are culture-positive for NTM with clinical suspicion of NTM-LD, serum sTREM-1 level measurements may be helpful in diagnosing and predicting outcome for NTM-LD.