Microbiology and molecular biology reviews : MMBR
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Microbiol. Mol. Biol. Rev. · Dec 2005
ReviewCoronavirus pathogenesis and the emerging pathogen severe acute respiratory syndrome coronavirus.
Coronaviruses are a family of enveloped, single-stranded, positive-strand RNA viruses classified within the Nidovirales order. This coronavirus family consists of pathogens of many animal species and of humans, including the recently isolated severe acute respiratory syndrome coronavirus (SARS-CoV). ⋯ The SARS-CoV part covers the pathogenesis of SARS, the developing animal models for infection, and the progress in vaccine development and antiviral therapies. The data gathered on the animal coronaviruses continue to be helpful in understanding SARS-CoV.