Scandinavian cardiovascular journal : SCJ
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Scand. Cardiovasc. J. · Aug 2002
Randomized Controlled Trial Clinical TrialUse of heparin-bonded circuits in cardiopulmonary bypass improves clinical outcome.
The use of heparin-coated surfaces in cardiopulmonary bypass has been shown to decrease the inflammatory response imposed by the contact between blood and artificial surfaces. One would expect this reaction to improve clinical outcome. However, this has been difficult to verify. This investigation is based on an aggregation of two randomized studies from our institution and highlights possible effects of heparin coating on a number of clinically oriented parameters. ⋯ Based on several indicators, the use of heparin coating in cardiopulmonary bypass is associated with improved clinical results.