Scandinavian cardiovascular journal : SCJ
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Scand. Cardiovasc. J. · Mar 2004
Randomized Controlled Trial Comparative Study Clinical TrialOff-pump CABG reduces complement activation but does not significantly affect peripheral endothelial function: a prospective randomized study.
Cardiac surgery initiates a systemic inflammatory response, which may affect endothelial function. The aim of this study was to investigate if off-pump CABG (OPCAB) reduces the postoperative inflammatory response and affects endothelial function less than conventional on-pump CABG. ⋯ OPCAB reduces complement activation compared with on-pump CABG but does not significantly affect TNF-alpha and IL-8 release or endothelial function.