Scandinavian cardiovascular journal : SCJ
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Scand. Cardiovasc. J. · Dec 2005
Randomized Controlled TrialLeukocyte depleting filter attenuates myocardial injury during elective coronary artery bypass surgery.
Ischemia-reperfusion injury secondary to leukocyte activation has been widely recognized as one of the most relevant mechanism leading to postoperative organ dysfunction occurring after a period of ischemia. The aim of the present study was to evaluate in a prospective, randomized study, the value of leukocyte depleting filter in patients undergoing elective coronary artery bypass surgery. ⋯ The results of this study suggest a myocardial protective effect of leukocyte filter in the setting of elective coronary artery bypass surgery.