Scandinavian cardiovascular journal : SCJ
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Scand. Cardiovasc. J. · Apr 2005
Randomized Controlled Trial Comparative Study Clinical TrialPeripheral blood monocyte activation during coronary artery bypass grafting with or without cardiopulmonary bypass.
The aim of this prospective, randomized study was to investigate the impact of coronary artery bypass grafting (CABG) on peripheral monocytes and to evaluate the additional effect of cardiopulmonary bypass (CPB). ⋯ It is concluded that the circulating monocyte population is activated during and as a consequence of CABG. There were few apparent additional effects of CPB found in this study. In this setting the inflammation caused by the surgery procedure per se probably surpasses the impact of the CPB on circulating blood monocytes.