Scandinavian cardiovascular journal : SCJ
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Scand. Cardiovasc. J. · Aug 2013
Polymorphisms and high on-aspirin platelet reactivity after off-pump coronary artery bypass grafting.
High on-aspirin residual platelet reactivity (RPR) after coronary artery bypass grafting (CABG) is a transient phenomenon with important implications for graft patency. This study was designed to determine the role of polymorphisms [TBXA2R (T924C), GPIIIa (Pl(A1/A2)), P2Y1 (A1622G), and GP1Bα (C1018T)] on RPR in Chinese patients undergoing off-pump CABG (OPCAB). ⋯ High on-aspirin RPR after OPCAB is associated with genetic polymorphism TBXA2R-924TT and obesity.
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Scand. Cardiovasc. J. · Aug 2013
Long-term left ventricular support in patients with a mechanical aortic valve.
The presence of a mechanical prosthesis has been regarded as an increased risk of thromboembolic complications and as a relative contraindication for a left ventricular assist device (LVAD). Five patients in our center had a mechanical aortic valve at the time of device implantation and were studied regarding thromboembolic complications. ⋯ The strategy of leaving a mechanical heart valve in place at the time of LVAD implantation in five patients led to valvular thrombosis in three but did not provoke embolic events. It increased the complexity of postoperative anticoagulation.
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Scand. Cardiovasc. J. · Aug 2013
Comparative Study Observational StudyAvoidance of noninfectious sternal dehiscence: figure-of-8 wiring is superior to straight wire closure.
Comparison of figure-of-8 wiring or simple straight-wiring technique assessed by the frequency of early noninfectious sternal dehiscence. ⋯ In a large cohort of consecutive cardiac operations, it was found that sternal closure with figure-of-8 wires is better than closure with simple interrupted wires.