Scandinavian cardiovascular journal : SCJ
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Scand. Cardiovasc. J. · Jun 2015
Randomized Controlled TrialRemote ischemic preconditioning and incidence of postoperative atrial fibrillation.
Although remote ischemic preconditioning (RIPC) has shown favorable effects on ischemia-reperfusion injury, much remains unknown of its mechanisms and clinical significance. We hypothesized that RIPC would reduce the incidence of postoperative atrial fibrillation (POAF) following coronary artery bypass graft (CABG) surgery. In addition, we investigated whether RIPC could induce alterations of circulating microRNA in blood plasma. ⋯ We did not observe a reduced incidence of POAF by RIPC before CABG surgery. Larger multi-center studies may be necessary to further clarify this issue.