Scandinavian cardiovascular journal : SCJ
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Scand. Cardiovasc. J. · Apr 2010
Comparative StudyInflammatory/oxidative stress during the first week after different types of cardiac surgery.
To compare inflammatory and oxidative stress time course during the first week after different types of cardiac surgery. ⋯ Cardiac surgery results in extensive and complex inflammatory/oxidative stress response regardless of the method or type of surgical procedure used. Myeloperoxidase could be one of the parameters to evaluate the cardiopulmonary bypass-associated inflammatory and oxidative stress response.
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Scand. Cardiovasc. J. · Apr 2010
Comparative StudyFondaparinux or enoxaparin: a comparative study of postoperative bleeding in coronary artery bypass grafting surgery.
Preoperative treatment with anti-coagulants for patients with non-ST-elevation acute coronary syndromes (NSTE-ACS) exposes patients undergoing surgical revascularization to a higher risk of perioperative bleeding. The aim of this study was to compare the effect on bleeding and transfusion needs during cardiac surgery for patients treated with enoxaparin or fondaparinux. ⋯ This study suggests that preoperative treatment with fondaparinux for NSTE-ACS is as safe as enoxaparin in terms of postoperative bleeding and transfusion needs. Findings support discontinuation of fondaparinux at 36 h prior to surgery.
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Scand. Cardiovasc. J. · Feb 2010
Multicenter StudyCatheter based closure of ventricular septal defects.
Catheter based treatment for heart diseases is increasing. Rikshospitalet has been the leading force in Norway to introduce such methods. We present the results of such treatment for different defects in the ventricular septum (VSD). ⋯ Catheter-based closure of VSD is a good alternative to open heart surgery. At present our own and the reported incidence of complete AV blocks lead us to be cautious when recommending closure of perimembranous VSD.
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Scand. Cardiovasc. J. · Feb 2010
A metabolic protective strategy could improve long-term survival in patients with LV-dysfunction undergoing CABG.
Adverse outcome after CABG is closely related to postoperative heart failure precipitated by ischemia and myocardial infarction. Restrictive use of inotropes is therefore desirable. Patients with preoperative left ventricular dysfunction are a high-risk group in this respect. To reduce myocardial oxygen expenditure we evolved a metabolic strategy for perioperative care. ⋯ The metabolic strategy allowed restrictive use of inotropes and was associated with encouraging long-term survival. Renal function was well preserved suggesting that SvO(2) served as an adequate marker of circulation. Randomized trials with metabolic support are warranted.
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Scand. Cardiovasc. J. · Aug 2009
Multicenter StudyTemporary circulatory support with extra corporeal membrane oxygenation in adults with refractory cardiogenic shock.
Early and long-term survival in patients suffering from cardiogenic shock is poor. Treatment with mechanical assist devices is complicated and expensive but claim to improve survival. We reviewed our experience of venoarterial extracorporeal membrane oxygenation (ECMO) in patients with acute cardiogenic shock. ⋯ Mortality for patients in cardiogenic shock is very high. Treatment with ECMO in patients with refractory cardiogenic shock can be performed with good survival especially in non-surgical patients.