Scandinavian cardiovascular journal : SCJ
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Scand. Cardiovasc. J. · Jun 2013
Randomized Controlled TrialSevoflurane at 1 MAC provides optimal myocardial protection during off-pump CABG.
We investigated the myocardial protective effect of sevoflurane in patients receiving off-pump coronary artery bypass grafting (OPCABG) and the role of brain natriuretic peptide (BNP). ⋯ Our results demonstrated that 1.0 MAC and 1.5 MAC sevoflurane can exert a significant myocardial protective effect. BNP cannot be used to predict the myocardial protective effect of sevoflurane in OPCABG.
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Scand. Cardiovasc. J. · Dec 2012
Randomized Controlled TrialDiazoxide may protect endothelial glycocalyx integrity during coronary artery bypass grafting.
Plasma hyaluronan and syndecan-1 levels represent shedding of the endothelium glycocalyx during ischemia and edema. Diazoxide, a K(ATP)-channel opener, has been shown to decrease myocardial edema during coronary artery bypass grafting (CABG). We evaluated whether diazoxide exerts an impact on plasma hyaluronan and syndecan-1 levels during CABG. ⋯ Diazoxide may have an impact on levels of peripheral plasma hyaluronan and syndecan-1 after CABG, suggesting decreased shedding of the endothelial glycocalyx layer.
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Scand. Cardiovasc. J. · Oct 2012
Randomized Controlled Trial Comparative StudyWake-up times following sedation with sevoflurane versus propofol after cardiac surgery.
Intravenous sedation in the intensive care unit (ICU) may contribute to altered consciousness and prolonged mechanical ventilation. We tested the hypothesis that replacing intravenous propofol with inhaled sevoflurane for sedation after cardiac surgery would lead to shorter wake-up times, quicker patient cooperation, and less delusional memories. ⋯ Sevoflurane sedation after cardiac surgery leads to shorter wake-up times and quicker cooperation compared to propofol. No differences were seen in ICU-stay, adverse memories or recovery events in our short-term sedation.
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Scand. Cardiovasc. J. · Oct 2011
Randomized Controlled TrialShort-term effects of inspiratory muscle training in coronary artery bypass graft surgery: a randomized controlled trial.
To investigate the efficiency of inspiratory muscle training (IMT) on postoperative respiratory muscle strength, functional capacity, quality of life, and psychosocial status in patients with coronary artery bypass graft (CABG) surgery. ⋯ IMT results in faster recovery of inspiratory muscle strength, functional capacity, intensive care unit stay, quality of life and psychosocial status after CABG.
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Scand. Cardiovasc. J. · Jun 2010
Randomized Controlled Trial Comparative StudyGraft patency after off-pump versus on-pump coronary artery surgery in high-risk patients.
To compare angiographic graft patency in high-risk patients randomly allocated to off-pump vs. on-pump coronary artery bypass grafting (CABG). ⋯ In patients with 3-vessel disease and a high-risk profile we found no statistically significant difference in graft patency between off-pump and on-pump CABG at 1-year coronary angiographic follow-up.