Clinical and experimental nephrology
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Clin. Exp. Nephrol. · Jun 2017
Randomized Controlled Trial Multicenter Study Comparative StudyDesign and baseline characteristics of the LANDMARK study.
Calcium (Ca)-based phosphate (P) binders, compared to non-Ca-based P binders, contribute to vascular calcification, which is associated with cardiovascular events. ⋯ The LANDMARK study will determine whether LC, a non-Ca-based P binder, reduces cardiovascular mortality and morbidity in chronic hemodialysis patients.