British journal of anaesthesia
-
Case Reports
Anatomical variations of the phrenic nerve and its clinical implication for supraclavicular block.
This paper reports a case of simultaneous diaphragmatic and brachial plexus stimulation followed by a successful nerve block using the supraclavicular approach. An explanation for the qualitative differences in phrenic nerve block between interscalene and supraclavicular block is postulated, based on known anatomical variations.
-
Randomized Controlled Trial Comparative Study Clinical Trial
Randomized, controlled, cross-over clinical trial comparing intravenous midazolam sedation with nitrous oxide sedation in children undergoing dental extractions.
The use of benzodiazepines for paediatric dental sedation has received limited attention with regard to research into clinical effectiveness. A study was therefore designed to investigate the use of midazolam, for i.v. sedation in paediatric dental patients. ⋯ I.V. midazolam sedation (0.5 mg x min(-1) to a maximum of 5 mg) appears to be as effective as nitrous oxide sedation in 12-16-yr-old healthy paediatric dental patients.
-
Randomized Controlled Trial Multicenter Study Clinical Trial
Randomized prospective study of the analgesic effect of nefopam after orthopaedic surgery.
Balanced postoperative analgesia combines non-narcotic drugs and opioids. We organized a large study to evaluate nefopam analgesia and tolerance in combination with morphine for patient-controlled analgesia (PCA) after orthopaedic surgery. ⋯ In combination with PCA morphine, nefopam gives significant morphine-sparing with lower immediate postoperative pain scores without major side-effects. This analgesic effect seems to be particularly notable for patients with intense preoperative pain.
-
Recent research into memory formation under sedation has generated conflicting results. We investigated explicit and implicit memory in ICU patients during moderate to deep propofol sedation following cardiac surgery. ⋯ We found no evidence for memory formation in post-cardiac surgery patients under moderate to deep propofol sedation.