British journal of anaesthesia
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Randomized Controlled Trial Clinical Trial
Effects of dexamethasone on clinical course, C-reactive protein, S100B protein and von Willebrand factor antigen after paediatric cardiac surgery.
Anti-inflammatory treatment with glucocorticoids during cardiopulmonary bypass can reduce inflammatory mediator release, but the effects of glucocorticoid on outcome are controversial. ⋯ Administration of dexamethasone before cardiopulmonary bypass for paediatric cardiac surgery decreased the inflammatory response, but did not affect the immediate features after surgery or changes in vWf:Ag or S100B.
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Randomized Controlled Trial Clinical Trial
Sedation caused by clonidine in patients with spinal cord injury.
In patients with spinal cord injury, cephalad spread of intrathecal (i.t.) medication could be delayed. ⋯ A systemic effect is likely to be the main reason for sedation.
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Randomized Controlled Trial Clinical Trial
Analgesic effects of parecoxib following total abdominal hysterectomy.
Forty-eight ASA I-II patients undergoing total abdominal hysterectomy (TAH) were studied in a double blind, randomized placebo controlled trial of parecoxib for postoperative analgesia. ⋯ Parecoxib 40 mg i.v. may be recommended in patients having TAH as it provides morphine-sparing analgesia.
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Letter Randomized Controlled Trial Clinical Trial
Repeated intranasal capsaicin applications to treat chronic migraine.