British journal of anaesthesia
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Randomized Controlled Trial Meta Analysis
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
Hip fracture surgery may be associated with substantial blood loss. This study was designed to assess the efficacy and safety of the use of tranexamic acid in hip fracture surgery for the reduction of erythrocyte transfusion. ⋯ In hip fracture surgery, tranexamic acid reduces erythrocyte transfusion but may promote a hypercoagulable state. Thus, further evaluation of safety is required before recommending the off-label use of tranexamic acid.