British journal of anaesthesia
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Review Meta Analysis
Regional anaesthesia to prevent chronic pain after surgery: a Cochrane systematic review and meta-analysis.
Epidural anesthesia may reduce post-thoracotomy chronic pain (OR 0.33) and paravertebral block reduce that following breast ca surgery (OR 0.37).
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Randomized Controlled Trial Comparative Study
Comparison of techniques for double-lumen endobronchial intubation: 90{degrees} or 180{degrees} rotation during advancement through the glottis.
Rotating through 180o assists intubation with a double lumen tube while reducing sore throat and vocal cord injuries.
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Review Meta Analysis Comparative Study
Efficacy of dexmedetomidine compared with midazolam for sedation in adult intensive care patients: a systematic review.
Patients in Intensive Care Unit (ICU) often require sedatives which commonly include midazolam and the more recently developed α2-receptor agonist, dexmedetomidine. It was our aim to compare the sedative and clinical effectiveness of dexmedetomidine vs midazolam in adults admitted to ICU, using an objective appraisal of randomized control trials. Medline, Embase, SCOPUS, Web of Knowledge, Cinhal, the United States National Library of Medicine, and the Cochrane Database of Systematic Reviews were searched using keywords: 'dexmedetomidine', 'midazolam', and 'intensive care'. ⋯ A final paper found that, of the eight occasions measured, patients on dexmedetomidine were more often within the target sedation range than patients on midazolam. The sedative benefits of dexmedetomidine vs midazolam remain inconclusive. While some secondary outcomes showed clinical effectiveness of dexmedetomidine, more research is needed to validate the findings of these studies.